Retatrutide — a next-generation investigational peptide tool for metabolic research

Position your lab at the forefront of metabolic and obesity research with retatrutide, a novel triple-receptor agonist that activates GLP-1, GIP, and glucagon receptors. Engineered for potent, multi-pathway modulation of energy balance, glucose homeostasis, and weight regulation, retatrutide enables researchers to probe combined incretin and glucagon signaling with a single, well-characterized molecule.

Key research advantages

• Mechanistic breadth: Simultaneous activation of GLP-1, GIP, and glucagon receptors allows study of integrated effects on appetite regulation, energy expenditure, hepatic metabolism, and insulin sensitivity — revealing interactions not accessible with single-receptor ligands.

• Robust pharmacology: Retatrutide has demonstrated strong, dose-dependent effects on body weight and glycemic control in preclinical and early clinical evaluations, making it a reliable probe for dose–response and mechanism-of-action studies.

• Translational relevance: Early human data indicate predictable metabolic responses, supporting translational studies from animal models to clinical hypotheses and biomarker development.

• Experimental versatility: Suitable for acute and chronic dosing paradigms to examine short-term signaling events, inter-organ crosstalk, or long-term adaptations in adipose tissue, liver, pancreas, and central nervous system circuits.

• Biomarker and pathway discovery: Use retatrutide to identify downstream molecular signatures (transcriptomic, proteomic, metabolomic), signaling cascades, and potential combination targets for future therapeutic strategies.

Suggested research applications

• Comparative pharmacology: Contrast single- and dual-agonists with retatrutide to deconvolute receptor-specific versus synergistic effects on appetite, body weight, and glucose regulation.

• Mechanisms of weight loss: Dissect contributions of reduced food intake versus increased energy expenditure and tissue-specific substrate utilization.

• Hepatic metabolism and NAFLD/NASH models: Investigate direct and indirect effects on hepatic lipid handling, inflammation, and fibrosis pathways.

• Islet biology and insulin dynamics: Examine effects on beta-cell function, insulin secretion dynamics, and incretin sensitivity.

• Central nervous system effects: Map hypothalamic and reward-circuit responses to combined incretin/glucagon signaling.

• Biomarker discovery for clinical translation: Identify peripheral and central biomarkers predictive of response or adverse effects.

Practical considerations for researchers

• Dosing and formulation: Establish dose-ranging studies to define receptor occupancy windows and separate central versus peripheral effects. Use appropriate vehicle and stability controls for peptide handling.

• Species selection: Consider interspecies differences in receptor pharmacology when designing translational experiments; include nonrodent models where receptor homology supports translation.

• Safety and tolerability endpoints: Monitor cardiovascular, hepatic, and metabolic safety markers in chronic studies given glucagon receptor activity.

• Combination studies: Evaluate interactions with lifestyle interventions, existing antidiabetic agents, or targeted modulators of energy balance.

• Analytical endpoints: Integrate metabolic phenotyping (indirect calorimetry, body composition), molecular assays, and imaging to capture multidimensional effects.

Available for research purposes

Transform skin recovery and rejuvenation with the GHK-Cu Prefilled Pen — a precise, convenient, and clinically inspired delivery system designed for professionals and informed consumers seeking reliable peptide therapy.

Why GHK-Cu?

• Potent, multi-action peptide: GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is well-studied for supporting collagen synthesis, improving skin firmness, accelerating wound healing, and reducing inflammation and oxidative stress.

• Evidence-backed results: Research demonstrates GHK-Cu’s ability to stimulate extracellular matrix production, promote fibroblast activity, and improve skin tone and elasticity with consistent use.

Why the Prefilled Pen?

• Accurate dosing: Each pen is calibrated to deliver a precise microdose every application, eliminating guesswork and ensuring consistent therapeutic exposure.

• Ready-to-use convenience: Sterile, single-use cartridges reduce preparation time and contamination risk. No mixing, no measuring—just reliable application.

• Ease of administration: Ergonomic design and intuitive dosing mechanism make it suitable for clinical use and for trained at-home administration when supervised by a provider.

• Portability and discretion: Compact, travel-friendly form factor lets patients continue treatment adherence with minimal disruption to their routines.

• Quality and stability: Formulated and filled under controlled conditions to preserve peptide integrity and potency throughout the recommended usage period.

Clinical and Cosmetic Benefits

• Faster recovery from procedures: Supports tissue repair and reduces downtime after microneedling, laser resurfacing, and minor surgical interventions.

• Improved skin architecture: Promotes collagen and elastin production to reduce fine lines, improve firmness, and restore youthful texture.

• Enhanced wound healing: Encourages efficient healing pathways and reduces scar formation risks.

• Anti-inflammatory and antioxidant support: Helps calm post-procedural erythema and oxidative damage for a clearer, healthier complexion.

Who should consider it?

• Aesthetic clinics and dermatology practices seeking a streamlined peptide solution for patient protocols.

• Practitioners offering post-procedure care to shorten recovery times and improve outcomes.

• Educated patients under provider guidance who want a professional-grade peptide treatment with consistent dosing.

Safety and guidance

• Available for research purposes

• Single-use cartridges and sterile packaging minimize infection risk. Follow storage

Selank is a synthetic heptapeptide developed to support cognitive function and emotional balance. Modeled on a naturally occurring immunomodulatory peptide, Selank is reported to reduce anxiety, improve attention and memory, and enhance stress resilience without the sedative effects associated with traditional anxiolytics. It is often administered as a nasal spray or by subcutaneous injection in research and clinical settings. Mechanistically, Selank is believed to modulate neurotransmitter systems (including serotonin and dopamine), upregulate brain-derived neurotrophic factor (BDNF), and exert mild immunoregulatory actions. Users commonly seek Selank for acute stress reduction, improved focus, and mood stabilization; reported side effects are typically minimal but can include mild local irritation or transient headaches. As with all research peptides, Selank should be used under appropriate medical guidance and in compliance with local regulations.

Unlock leaner composition, improved metabolic health, and renewed confidence with Tesamorelin — the clinically studied peptide therapy designed to reduce visceral fat and support healthier aging.

What Tesamorelin

• Targets abdominal (visceral) fat: Tesamorelin stimulates natural growth hormone–releasing pathways to specifically reduce harmful visceral adipose tissue, the fat linked to metabolic disease and cardiovascular risk.

• Supports metabolic markers: Clinical evidence shows reductions in waist circumference and improvements in body composition that can positively influence metabolic health.

• Preserves lean mass: By promoting endogenous growth hormone secretion rather than administering exogenous hormone, Tesamorelin helps protect muscle while targeting unwanted deep abdominal fat.

• Fast, predictable results: Many patients see measurable reductions in visceral fat within months when used as part of a medically supervised program that includes nutrition and exercise.

Why choose Tesamorelin

• Clinically validated: Tesamorelin has been evaluated in randomized controlled trials demonstrating meaningful reductions in visceral adiposity and waist circumference.

• Well-defined mechanism: Works through growth hormone–releasing factor pathways to stimulate physiologic GH release, offering a targeted approach to visceral fat that differs from general weight-loss drugs.

• Complementary to lifestyle medicine: Best used as part of a comprehensive plan — nutrition, exercise, and metabolic monitoring — to maximize durable outcomes.

• Streamlined administration: Supplied as a subcutaneous injectable with established dosing protocols, enabling straightforward incorporation into your treatment offerings under medical oversight.

Available for research purposes

Retatrutide is an experimental, once-daily injectable peptide drug designed to promote weight loss by activating multiple hormone receptors involved in appetite and metabolism. As a triple agonist targeting GLP-1, GIP, and glucagon receptors, retatrutide aims to reduce food intake, increase energy expenditure, and improve glucose control. Early clinical trials have shown substantial average reductions in body weight in adults with obesity, along with improvements in metabolic markers such as fasting glucose and lipid profiles. Commonly reported side effects mirror those of other incretin-based therapies and include gastrointestinal symptoms (nausea, vomiting, diarrhea) and potential transient increases in heart rate. Retatrutide remains under clinical investigation; safety, optimal dosing, and long-term effects are still being evaluated.

MOTS-C 10mg Pre-Filled Pen

A ready-to-use, precision-dosed peptide pen delivering MOTS-C—an advanced mitochondrial-derived peptide designed to support cellular metabolism and metabolic wellness. Each pen contains a sterile, pre-measured dose of MOTS-C in a stabilized formulation for consistent administration without the need for reconstitution, measuring, or vial handling.

Key benefits

• Metabolic support: Formulated to promote healthy cellular energy regulation and metabolic function.

• Consistent dosing: Factory pre-filled and calibrated for accurate, repeatable administration every use.

• Ease of use: Pen delivery system simplifies self-administration; no mixing or drawing required.

• Sterile and stable: Manufactured under aseptic conditions and formulated for stability over the labeled shelf life when stored per instructions.

• Discreet and convenient: Compact design for convenient daily use or travel.

Available for research purposes only